David A. Scheinberg, MD, PhD, is Chair of the Center for Experimental Therapeutics and the Vincent Astor Chair at Memorial Sloan Kettering Cancer Center (MSKCC), where he treats patients with leukemia. Dr. Scheinberg also serves as Chair of the Molecular Pharmacology Program at the Sloan Kettering Institute. He is a professor of medicine and of pharmacology at Weill Cornell Medical College and a founder and director of the Therapeutics Discovery Institute, a joint effort of Weill Cornell, the Rockefeller University, and MSKCC.
Dr. Scheinberg’s research is focused on discovering and developing novel, specific immunotherapeutic agents and to understand their mechanisms of action as well as the mechanisms of resistance to them. Eight different therapeutic agents developed in Dr. Scheinberg’s laboratory have reached human clinical trials. His laboratory is also investigating cellular resistance mechanisms to these agents.
Dr. Scheinberg received his bachelor’s degree from Cornell University and his MD and PhD in pharmacology and experimental therapeutics from the Johns Hopkins University School of Medicine.
Jedd D. Wolchok, MD, PhD is Chief of the Melanoma and Immunotherapeutics Service at Memorial Sloan Kettering Cancer Center (MSKCC); an associate director of the Ludwig Center for Cancer Immunotherapy at MSKCC, an associate member of Ludwig Cancer Research, and the Lloyd J. Old/Virginia and Daniel K. Ludwig Chair in Clinical Investigation at MSKCC. He is director of the CRI/Ludwig Cancer Vaccine Collaborative Trials Network, and is an associate director of the CRI Scientific Advisory Council. He is also the co-director of the Swim Across America laboratory at MSKCC, one of the foremost immunotherapy and melanoma research groups in the country.
His specific research interest is the pre-clinical and early clinical development of novel immunologic therapies. Most recently, Dr. Wolchok has initiated several clinical trials using plasmid DNA vaccines for patients with melanoma.
Dr. Wolchok has authored numerous articles concerning DNA vaccines, cytokine biology, and clinical care of melanoma and co-authored two chapters in the definitive textbook, Cutaneous Melanoma. Dr. Wolchok is also co-editor of the journal Cytotherapy.
Dr. Jeffrey Weber, a specialist in cancer immunotherapy, is currently deputy director of the Perlmutter Cancer Center and the co-director of the Melanoma Research Program at the New York University (NYU)-Langone Cancer Center. Dr. Weber is principal investigator on several ongoing studies funded by the National Cancer Institute (NCI) as well as industry, including trials in clinical drug development, vaccines, and studies on autoimmunity and melanoma. He earned his PhD in molecular biology from Rockefeller University (NY) in 1979 and his MD from New York University in 1980. Dr. Weber sat on the NCI’s Clinical Oncology Study section as well as the boards of the Melanoma Research Foundation and the Melanoma Therapeutics Foundation, and served as a chair of the Veterans Administration’s clinical oncology study section. He has published more than 150 articles in the top peer-reviewed journals in his field.
Alexander M.M. Eggermont is currently the Director General of Institut Gustave Roussy Cancer Campus Grand Paris, Villejuif, France, as well as Professor of Oncology at the University Paris-Sud. He is the past Professor of Surgical Oncology and current Professor of International Networking in Cancer Research at the Erasmus University Medical Centre in Rotterdam. He holds the honorary Chair of Surgical Oncology at the Catholic University of Louvain, Belgium. Prof. Eggermont is a past President of the European Cancer Organisation and European Organisation for Research and Treatment of Cancer (EORTC) and past Chair of the EORTC Melanoma Group. He is the current President of the European Academy of Cancer Sciences, the chairman of Cancer Core Europe and Chair of the International Jury for Comprehensive Cancer Centre Program in Germany, as well as board member of the European Society for Medical Oncology. He obtained his MD at the University of Amsterdam and PhD in tumor immunology at the Erasmus University in Rotterdam, both in the Netherlands, and was a Fellow of the NCI Surgery Branch in Bethesda, MD, USA. He has published more than 800 peer reviewed publications.
Larry W. Kwak, MD, PhD is Cancer Center Associate Director, Translational Research & Developmental Therapeutics for the City of Hope National Medical Center, Director of the Toni Stephenson Lymphoma Center within the Hematologic Malignancies and Stem Cell Transplantation Institute, and is endowed with the title of the Dr. Michael Friedman Professor in Translational Medicine. From 2004 to 2014, Dr. Kwak served as Chairman of the Department of Lymphoma and Myeloma and Co-Director of the Center for Cancer Immunology Research at the University of Texas, M.D. Anderson Cancer Center in Houston, Texas, where he also held the Jane and John Justin Distinguished Chair in Leukemia Research. Prior to his role at M.D. Anderson, Dr. Kwak served as Head of the Vaccine Biology Section, Experimental Transplantation and Immunology Branch, at the National Cancer Institute for 12 years. His laboratory at the NCI was credited with the bench-to-clinic development of a therapeutic cancer vaccine for B-cell malignancies. In 2010, Kwak was named to TIME Magazine’s TIME100 as one of the world’s 100 most influential people for his 20-year commitment to the science of cancer vaccines, specifically a personalized therapy for follicular lymphoma. Dr. Kwak received his medical degree from Northwestern University Medical School and earned his Ph.D. in tumor cell biology there in 1984. He also completed a residency in internal medicine and a fellowship in medical oncology at Stanford University Medical Center in California.
Dr. Javier Pinilla-Ibarz has a long track record of successfully applying immunology clinical and translational approaches to the treatment of leukemias and myelodysplastic syndromes. He is currently an associate member of the malignant hematology and immunology program and Director of Immunotherapy for Malignant Hematology at the H. Lee Moffitt Cancer Center, as well as an associate professor in the Department of Oncologic Sciences, University of South Florida College of Medicine, both in Tampa, FL. Dr. Pinilla-Ibarz received his MD and then PhD degrees from the University of Zaragoza, Spain. He then completed a research fellowship in Immunology at the Memorial Sloan-Kettering Cancer Center, as well as a Hematology and Oncology training at the same Institution. Dr. Pinilla-Ibarz has published more than 100 articles in the top peer-reviewed journals in his field.
Sattva Neelapu, MD, PhD, serves as an Associate Professor of Department of Lymphoma and Myeloma, Division of Cancer Medicine at The University of Texas M.D. Anderson Cancer Center.
Dr. Neelapu laboratory is focused on characterization of immune-regulatory mechanisms in the tumor microenvironment in patients with lymphoma and development of novel therapeutic strategies for patients with lymphoma. His research is supported and recognized by numerous awards from national and international organizations including the National Institutes of Health, American Society of Clinical Oncology, American Association for Cancer Research, American Society of Hematology, Doris Duke Charitable Foundation, and Leukemia and Lymphoma Society
Dr. Neelapu obtained his medical degree in India and subsequently moved to the United States of America where he completed residency in Internal Medicine at Coney Island Hospital, Brooklyn, New York, and clinical fellowship in Medical Oncology and postdoctoral fellowship in tumor immunology and immunotherapy at the National Cancer Institute, National Institutes of Health, Bethesda, Maryland.