We are a late-stage clinical biopharmaceutical company focused on the development of novel therapeutics for a broad range of cancer indications. Our product candidates currently include galinpepimut-S, or GPS, a cancer immunotherapeutic agent that targets the Wilms tumor 1, or WT1, protein, and SLS009, a highly selective small molecule cyclin-dependent kinase 9, or CDK9, inhibitor.
SELLAS’ cancer programs target diverse indications in hematological cancers and solid tumors.
Dr. Sattva Neelapu serves as a Professor and Deputy Department Chair at the Department of Lymphoma and Myeloma, Division of Cancer Medicine at The University of Texas M.D. Anderson Cancer Center in Houston, TX.
Dr. Neelapu’s laboratory is focused on characterization of immune-regulatory mechanisms in the tumor microenvironment in patients with lymphoma and development of novel therapeutic strategies for patients with lymphoma. Dr. Neelapu’s clinical research has focused on the development of therapeutic vaccines for lymphoid malignancies and he has conducted some of the first immune checkpoint inhibitor trials in lymphoma. Most recently, his work on the pivotal trial of axicabtagene ciloleucel CD 19 CAR T-cell therapy in aggressive B-cell lymphoma led to its FDA approval as the first CAR-T therapy for lymphoma. His research is supported and recognized by numerous awards from national and international organizations including the National Institutes of Health, American Society of Clinical Oncology, American Association for Cancer Research, American Society of Hematology, Doris Duke Charitable Foundation, and Leukemia and Lymphoma Society. Dr. Neelapu has been also awarded the Outstanding Achievement Award by the Indo-American Cancer Association (IACA), as well as the Excellence in Oncology Award by Oncology Times.
Dr. Neelapu obtained his medical degree in India and subsequently moved to the United States where he completed residency in Internal Medicine at Coney Island Hospital, Brooklyn, New York, and a clinical fellowship in Medical Oncology and postdoctoral fellowship in tumor immunology and immunotherapy at the National Cancer Institute (NCI) in Bethesda, Maryland. Dr. Neelapu has published more than 200 peer reviewed journal articles, textbook chapters and monographs.